Speaker
Description
Three-dimensional (3D) printing technology is capable of creating highly complex, customizable objects, offering unique advantages for various biomedical applications through methods such as inkjet-based, extrusion-based, and light-assisted techniques. This study focuses on using direct ink writing for additive manufacturing to print antibacterial wound dressings, addressing a critical gap in the current wound care market. The management of chronic and acute wounds presents significant challenges facing human health and overall wellness, resulting in decreased quality of life. Current wound dressing fails to meet patients’ needs in terms of high adhesion, poor gas exchange, low moisture retention, and the use of systemic and synthetic antibiotics. Additionally, the presence of unused agricultural waste and weak waste management increase greenhouse gas emissions, thus contributing to global warming. To address these issues, we utilized agricultural waste, specifically sugarcane bagasse, to create biopolymer 3D printing ink for wound dressings. We extracted cellulose from sugarcane bagasse and antibacterial bioactive compounds from plant extracts. The synthesized ink was then printed and post treated to enhance mechanical properties. We evaluated the cytotoxicity, antibacterial activity, and morphological structure of the patches using scanning electron microscopy and determined their elemental composition through energy dispersive X-ray analysis. Our primary analysis revealed several key points: the biocompatibility of the patches, their proliferated structure, and the need to enhance the antibacterial agents used. This exploration of new materials and antibacterial agents is crucial for advancing the wound care market, benefiting both patients and the environment.
Keywords: Additive Manufacturing, Agricultural Waste, Wound Management, Cellulose
